The Los Angeles Rams will take on the San Francisco 49ers at Levi’s Stadium on Thursday night, to kick off the NFL Week 15. The Los Angeles Rams are second in the NFC West after winning seven games and losing six so far in the season. Meanwhile, the San Francisco 49ers are fourth in the table with a current 6-7 record. While the Rams hope to build on their winning streak, the latest NFL betting odds favor the San Francisco 49ers to win here.
The preview information
Date: December 12, Thursday | Time: 8:15 p.m. Eastern Time
Location: Levi’s Stadium, Santa Clara, California
TV: Amazon Prime Video
Stream: NFL+/Fubo TV
Los Angeles Rams Vs San Francisco 49ers Odds, Spread, Moneyline
Moneyline: Los Angeles Rams (+110) vs San Francisco 49ers (-130)
Spread: Los Angeles Rams +2 (-110) vs San Francisco 49ers -2 (-110)
Total (O/U): Los Angeles Rams (o49) vs San Francisco 49ers (u49)
*All odds are subject to change depending on the time of this posting

Los Angeles Rams
The Los Angeles Rams locked horns with the Buffalo Bills before this and won the game with a close score of 44-42. Against Buffalo, LA’s QB Matthew Stafford went for 320 yards, completing 23 passes out of 30, scoring twice. Kyren Williams managed the rushing with 29 carries for 87 yard, along with a pair of TDs. On defense, Puka Nacua managed 12 receptions for 162 yards, scoring once.
Players to watch:
Matthew Stafford: 3,303 Yds, 19 TD, 7 INT
Kyren Williams: 251 Car, 1,013 Yds, 12 TD
Puka Nacua: 54 Rec, 708 Yds, 3 TD
San Francisco 49ers
The San Francisco 49ers are coming here after playing the Chicago Bears in the previous matchup. In that game, San Francisco won with a final score of 38-13, after QB Brock Purdy attempted 25 passes and completed 20 for 325 yards. Purdy managed to score twice against the Bears. In terms of rushing, Isaac Guerendo managed 15 carries for 78 yards, along with a pair of TDs, while George Kittle defended with six receptions for 151 yards.
Players to watch:
Brock Purdy: 3,032 Yds, 15 TD, 8 INT
Jordan Mason: 153 Car, 789 Yds, 3 TD
Jauan Jennings: 57 Rec, 774 Yds, 6 TD

Los Angeles Rams Vs San Francisco 49ers Injury Report
Los Angeles Rams
John Johnson III (S) IR, Shoulder
Conor McDermott (T) IR, Undisclosed
Joseph Noteboom (T) IR, Ankle
Troy Reeder (LB) IR, Hamstring
Larrell Murchison (DT) IR, Arm
Tony Fields II (LB) IR, Ankle
Tre’Vius Hodges-Tomlinson (CB) IR, Undisclosed
KT Leveston (G) IR, Ankle
San Francisco 49ers
Trent Williams (T) Is “?” Thursday vs LA Rams, Ankle
Tashaun Gipson Sr. (S) Is out indefinitely, Suspension
Javon Hargrave (NT) Is out for season, Triceps
Christian McCaffrey (RB) IR, Knee
George Odum (S) Is “?” Thursday vs LA Rams, Undisclosed
Nick Bosa (DE) Is “?” Thursday vs LA Rams, Hip
Mitch Wishnowsky (P) IR, Back
Kevin Givens (DT) IR; is out for season, Pectoral
Brandon Aiyuk (WR) IR; is out for season, ACL
Aaron Banks (G) Is “?” Thursday vs LA Rams, Concussion
Ambry Thomas (CB) IR, Undisclosed
Eli Mitchell (RB) IR, Hamstring
Curtis Robinson (LB) Is out for season, ACL
Jordan Mason (RB) IR, Ankle
Jake Moody (K) Is out indefinitely, Ankle
Darrell Luter Jr. (CB) IR, Pelvis
Tatum Bethune (LB) IR, Knee
Isaac Guerendo (RB) Is “?” Thursday vs LA Rams, Foot

Los Angeles Rams Vs San Francisco 49ers Betting Trends
Los Angeles Rams
LA Rams are 5-2 ATS in their last 7 games.
LA Rams are 6-2 SU in their last 8 games.
LA Rams are 3-7 ATS in their last 10 games against San Francisco.
LA Rams are 3-9 SU in their last 12 games against San Francisco.
LA Rams are 1-4 SU in their last 5 games when playing on the road against San Francisco.
LA Rams are 6-1 SU in their last 7 games against an opponent in the National Football Conference West division.
LA Rams are 7-1 ATS in their last 8 games played in December.
The total has gone UNDER in 4 of LA Rams’ last 5 games played in week 15.
LA Rams are 6-1 ATS in their last 7 games played on a Thursday.
San Francisco 49ers
San Francisco are 1-4 ATS in their last 5 games.
The total has gone OVER in 4 of San Francisco’s last 5 games against LA Rams.
San Francisco are 4-10 ATS in their last 14 games at home.
San Francisco are 4-1 SU in their last 5 games when playing at home against LA Rams.
San Francisco are 3-9 ATS in their last 12 games against an opponent in the National Football Conference.
San Francisco are 1-4 SU in their last 5 games against an opponent in the National Football Conference West division.
The total has gone OVER in 6 of San Francisco’s last 8 games played in week 15.
The total has gone UNDER in 6 of San Francisco’s last 9 games played on a Thursday when at home.
Los Angeles Rams Vs San Francisco 49ers Summary and Prediction
The Los Angeles Rams are boasting lesser injuries and an abominable offense when compared to the 49ers here. However, San Francisco will play well at home and will use their confidence from their previous clash to win here. Take the San Francisco 49ers to win, 24-21.
Moneyline: 49ers (-130)
Spread: Under 2
Total: Under 49
Predicted Score: 24-21, 49ers win.

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