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Sep 15, 2024; Minneapolis, Minnesota, USA; San Francisco 49ers quarterback Brock Purdy (13) dives against the Minnesota Vikings in the third quarter at U.S. Bank Stadium. Mandatory Credit: Brad Rempel-Imagn Images

San Francisco 49ers vs Los Angeles Rams Prediction, Odds, Moneyline 09/22/2024 | 2024-2025 NFL Season

The San Francisco 49ers will meet the Los Angeles Rams for week 3 NFL this Sunday evening at SoFi Stadium. The San Francisco 49ers are third in the NFC West with an even 1-1 current record, while the Los Angeles Rams are one position lower with 0-2 on their record. The Rams are eager to break their losing streak and grab their first win of the season. But, the best NFL betting odds for this game are predicting the San Francisco 49ers to win.

 

The preview information

Date: September 22, Sunday | Time: 4:25 p.m. Eastern Time

Location: SoFi Stadium, Los Angeles

TV: FOX

Stream: NFL+/Fubo TV

 

San Francisco 49ers vs Los Angeles Rams Odds, Spread, Moneyline

Moneyline: San Francisco 49ers (-350) vs Los Angeles Rams (+280)

Spread: San Francisco 49ers (-7 – 115) vs Los Angeles Rams (+7 -105)

Total (O/U): San Francisco 49ers (u44.5) vs Los Angeles Rams (o44.5)

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Sep 15, 2024; Minneapolis, Minnesota, USA; San Francisco 49ers quarterback Brock Purdy (13) dives against the Minnesota Vikings in the third quarter at U.S. Bank Stadium. Mandatory Credit: Brad Rempel-Imagn Images

San Francisco 49ers

The San Francisco 49ers took on the Minnesota Vikings in the previous week and lost the game 23-17. Against the Vikings, San Francisco’s Brock Purdy attempted 36 passes and completed 28 for a total of 319 yards. Purdy went on to score a single touchdown along with a lone interception. Jordan Mason led the rushing with 20 carries for 100 yards and a single score. On defense, the 49ers had Deebo Samuel Sr. manage eight receptions for 110 yards.

Top 3 Players

Brock Purdy: 550 Yds, 1 TD, 1 INT

Jordan Mason: 48 Car, 247 Yds, 2 TD

Deebo Samuel Sr.: 13 Rec, 164 Yds, 0 TD

 

Los Angeles Rams

The Los Angeles Rams are coming to this week after playing the Arizona Cardinals last time out and losing miserably 41-10. In that disappointing game, LA’s QB Matthew Stafford attempted 27 passes and completed 19 for 216 yards. Blake Corum led the team’s rushing with eight carries for 28 yards. Defense-wise, the Los Angeles Rams had Demarcus Robinson contributing two receptions for 50 yards.

Top 3 Players

Matthew Stafford: 533 Yds, 1 TD, 1 INT

Kyren Williams: 30 Car, 75 Yds, 2 TD

Cooper Kupp: 18 Rec, 147 Yds, 1 TD

 

San Francisco 49ers vs Los Angeles Rams Injury Report

 

San Francisco 49ers

Jon Feliciano (G) IR, Undisclosed

Christian McCaffrey (RB) IR, Calf

George Kittle (TE) Is probable Sunday vs LA Rams, Dehydration

Deebo Samuel (WR) Is out indefinitely, Calf

Ambry Thomas (CB) IR, Undisclosed

Talanoa Hufanga (S) Is “?” Sunday vs LA Rams, Knee

Eli Mitchell (RB) IR, Hamstring

Kalia Davis (DT) IR, Knee

Dee Winters (LB) Is “?” Sunday vs LA Rams, Ankle

 

Los Angeles Rams

John Johnson III (S) IR, Shoulder

Cooper Kupp (WR) Is out indefinitely, Ankle

Conor McDermott (T) IR, Undisclosed

Joseph Noteboom (T) IR, Ankle

Darious Williams (CB) IR, Undisclosed

Jonah Jackson (G) IR, Undisclosed

Larrell Murchison (DT) IR, Arm

Davis Allen (TE) Is “?” Sunday vs San Francisco, Back

Tre’Vius Hodges-Tomlinson (CB) IR, Undisclosed

Puka Nacua (WR) IR, Knee

KT Leveston (G) IR, Ankle

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Sep 15, 2024; Glendale, Arizona, USA; Los Angeles Rams quarterback Matthew Stafford (9) throws in the first half against the Arizona Cardinals at State Farm Stadium. Mandatory Credit: Matt Kartozian-Imagn Images

San Francisco 49ers vs Los Angeles Rams Betting Trends

 

San Francisco 49ers

San Francisco are 1-5 ATS in their last 6 games.

The total has gone OVER in 8 of San Francisco’s last 12 games.

San Francisco are 10-4 SU in their last 14 games.

San Francisco are 7-2 ATS in their last 9 games against LA Rams.

San Francisco are 9-2 SU in their last 11 games against LA Rams.

San Francisco are 5-2 ATS in their last 7 games on the road.

San Francisco are 5-1 ATS in their last 6 games when playing on the road against the LA Rams.

San Francisco are 16-4 SU in their last 20 games against an opponent in the National Football Conference.

San Francisco are 12-1 SU in their last 13 games against an opponent in the National Football Conference West division.

The total has gone UNDER in 6 of San Francisco’s last 8 games played in September.

 

Los Angeles Rams

LA Rams are 7-3 ATS in their last 10 games.

The total has gone OVER in 7 of LA Rams’ last 10 games.

The total has gone OVER in 4 of LA Rams’ last 6 games against San Francisco.

LA Rams are 5-1 SU in their last 6 games at home.

LA Rams are 1-5 ATS in their last 6 games when playing at home against San Francisco.

The total has gone OVER in 4 of LA Rams’ last 6 games against an opponent in the National Football Conference.

LA Rams are 4-1 SU in their last 5 games against an opponent in the National Football Conference West division.

The total has gone UNDER in 4 of LA Rams’ last 6 games played in September.

LA Rams are 4-1-1 ATS in their last 6 games played in week 3.

 

San Francisco 49ers vs Los Angeles Rams Summary and Prediction

The Los Angeles Rams are presently one of the worst teams in the season, and are getting antsy to win. The 49ers are eager to redeem themselves after their defeat in week 2. As per the latest NFL betting trends, the San Francisco 49ers will win, 24-22 this Sunday.

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Sep 15, 2024; Minneapolis, Minnesota, USA; San Francisco 49ers tight end George Kittle (85) and wide receiver Brandon Aiyuk (11) and tight end Eric Saubert (82) react after a touchdown by Kittle during the second quarter against the Minnesota Vikings U.S. Bank Stadium. Mandatory Credit: Jeffrey Becker-Imagn Images

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Follow me on X at @ErnestLeo, and follow us at @HardwoodHeroics and @GridironHeroics. You can also reach out to Ernest Hernandez via email at ernestleo@gmail.com. To read more of our articles and keep up to date on the latest sports news, click here!

Ernest also handles a YouTube account called Sports On Air with over 102 thousand subscribers. The channel contains interviews predominantly from the Philippine Basketball Association. They can be reached at sportsonairph@gmail.com.

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About Ernest Leo Hernandez

Ernest has been a sportswriter for more than 10 years and has written for the top broadsheets in the Philippines, like Manila Bulletin and Philippine Star. He also wrote for NBA.com Philippines and had a two-year stint with Sportskeeda before landing at Gridiron Heroics. Aside from writing, Ernest is also a sportscaster, radio host and manages a YouTube channel, Sports On Air, which has over 100 thousand subscribers.

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