On Sunday night, the Detroit Lions will meet the Houston Texans at NRG Stadium to continue the NFL Week 10 schedule. The Detroit Lions are ruling the NFC North, after winning seven games and losing only one. The Houston Texans, meanwhile, are at the top of the AFC South, and are coming here after winning six games and losing three in the season. As per the best NFL betting odds, the Detroit Lions will win this matchup.
The preview information
Date: November 10, Sunday | Time: 8:20 p.m. Eastern Time
Location: NRG Stadium, Houston, Texas
TV: NBC
Stream: NFL+/Fubo TV
Detroit Lions Vs Houston Texans Odds, Spread, Moneyline
Moneyline: Detroit Lions (-188) vs Houston Texans (+164)
Spread: Detroit Lions -3.5 (-105) vs Houston Texans +3.5 (-107)
Total (O/U): Detroit Lions (o49) vs Houston Texans (u49)
*All odds are subject to change depending on the time of this posting

Detroit Lions
The Detroit Lions were paired with the Green Bay Packers for NFL Week 9 and won the game with a final score of 24-14. Against the Packers, Detroit’s offense was led by QB Jared Goff who managed 145 yards, completing 18 passes out of 22 attempts, along with a single TD. David Montgomery took charge of the team’s rushing with 17 carries for 73 yards, while Amon-Ra St. Brown defended the Lions with seven receptions for 56 yards, with a single score.
Top 3 Players
Jared Goff: 1,840 Yds, 14 TD, 4 INT
Jahmyr Gibbs: 103 Car, 656 Yds, 7 TD
Amon-Ra St. Brown: 48 Rec, 464 Yds, 6 TD
Houston Texans
The Houston Texans are coming here after playing the New York Jets in the previous matchup. Against the Jets, Houston lost the game 21-13 after QB C.J. Stroud attempted 30 passes and completed 11 for a total of 191 yards. Houston was led in rushing by Joe Mixon who managed 24 carries for 106 yards, scoring once. In terms of defense, the Texans had Tank Dell contributing six receptions for 126 yards.
Top 3 Players
C.J. Stroud: 2,139 Yds, 11 TD, 4 INT
Joe Mixon: 126 Car, 609 Yds, 6 TD
Nico Collins: 32 Rec, 567 Yds, 3 TD
Detroit Lions Vs Houston Texans Injury Report
Detroit Lions
Kyle Peko (DT) IR, Pectoral
Jalen Reeves-Maybin (LB) Injured last game, is “?” Sunday vs Houston, Shoulder
Marcus Davenport (DE) Is out for season, Elbow
Michael Badgley (K) IR; is out for season, Hamstring
Emmanuel Moseley (CB) IR, Pectoral
Netane Muti (G) IR, Shoulder
Derrick Barnes (LB) Is out indefinitely, Knee
Aidan Hutchinson (DE) IR; is out for season, Leg
Jameson Williams (WR) Is upgraded to probable Sunday vs Houston, Suspension Served
Josh Paschal (DE) Is “?” Sunday vs Houston, Illness
Malcolm Rodriguez (LB) Is “?” Sunday vs Houston, Ankle
Brodric Martin (DT) IR, Leg
Antoine Green (WR) IR, Concussion
Connor Galvin (T) IR, Knee
Christian Mahogany (G) Is “?” Sunday vs Houston, Illness
Sione Vaki (S) Is “?” Sunday vs Houston, Knee
Mekhi Wingo (DT) Is “?” Sunday vs Houston, Ankle
Nate Lynn (LB) IR, Shoulder
Houston Texans
Jerry Hughes (DE) IR, Hip
Case Keenum (QB) IR, Foot
Jimmie Ward (S) Is “?” Sunday vs Detroit, Groin
Stefon Diggs (WR) IR; is out for season, ACL
Azeez Al-Shaair (LB) Is “?” Sunday vs Detroit, Knee
Jeff Okudah (CB) IR, Hip
Dalton Keene (TE) IR, Knee
Nico Collins (WR) IR, Hamstring
Brevin Jordan (TE) IR; is out for season, ACL
Kenyon Green (G) Is out indefinitely, Shoulder
Christian Harris (LB) IR, Calf
Dameon Pierce (RB) Is “?” Sunday vs Detroit, Groin
Teagan Quitoriano (TE) IR, Calf
Will Anderson Jr. (DE) Left last game, is “?” Sunday vs Detroit, Ankle
Brandon Hill (S) IR, Leg
Jarrett Patterson (C) Is “?” Sunday vs Detroit, Concussion
Jaylon Thomas (G) IR, Undisclosed
Jawhar Jordan (RB) IR, Undisclosed
British Brooks (RB) IR, Knee

Detroit Lions Vs Houston Texans Betting Trends
Detroit Lions
Detroit are 6-0 ATS in their last 6 games.
The total has gone OVER in 4 of Detroit’s last 5 games.
Detroit are 6-0 SU in their last 6 games.
Detroit are 1-4 SU in their last 5 games against Houston.
Detroit are 7-0 ATS in their last 7 games on the road.
Detroit are 8-1 ATS in their last 9 games against an opponent in the American Football Conference.
The total has gone OVER in 5 of Detroit’s last 5 games against an opponent in the American Football Conference South division.
Detroit are 6-2 SU in their last 8 games played in November.
The total has gone OVER in 5 of Detroit’s last 7 games played in week 10.
Houston Texans
The total has gone UNDER in 7 of Houston’s last 8 games.
Houston are 9-4 SU in their last 13 games.
The total has gone OVER in 4 of Houston’s last 5 games against Detroit.
Houston are 6-0 SU in their last 6 games at home.
The total has gone UNDER in 9 of Houston’s last 11 games against an opponent in the National Football Conference.
The total has gone UNDER in 4 of Houston’s last 5 games against an opponent in the National Football Conference North division.
Houston are 1-6 ATS in their last 7 games played in November.
Houston are 7-2 ATS in their last 9 games played in week 10.
Houston are 4-1 SU in their last 5 games played on a Sunday.
Detroit Lions Vs Houston Texans Summary and Prediction
The Detroit Lions are having a pretty fantastic season so far, and will win quite comfortably in this matchup. The Texans are doing decently, but need to step up their game at home. The top NFL Week 10 betting picks predict the Detroit Lions to win, 27-13.
Moneyline: Lions (-188)
Spread: Under 3.5
Total: Over 49
Predicted Score: 27-13, Lions win.

For more sports content:
Follow me on X at @ErnestLeo, and follow us at @HardwoodHeroics and @GridironHeroics. You can also reach out to Ernest Hernandez via email at ernestleo@gmail.com. To read more of our articles and keep up to date on the latest sports news, click here!
Ernest also manages a YouTube account called Sports On Air with over 103 thousand subscribers. The channel contains interviews predominantly from the Philippine Basketball Association. They can be reached at sportsonairph@gmail.com.