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Buffalo Bills Vs Indianapolis Colts Prediction, Odds, Moneyline 11/10/2024 | 2024-2025 NFL Season

The Buffalo Bills are scheduled to take on the Indianapolis Colts at Lucas Oil Stadium this Sunday afternoon to continue the NFL season. The Buffalo Bills are at the top of the AFC East after winning seven games and losing two. Meanwhile, the Indianapolis Colts are ranked no. 2 in the AFC South with an overall 4-5 record on the season. The top NBA Week 10 betting experts predict the Buffalo Bills to grab a win in this matchup.

 

The preview information

Date: November 10, Sunday | Time: 1:00 p.m. Eastern Time

Location: Lucas Oil Stadium, Indianapolis, Indiana

TV: CBS

Stream: NFL+/Fubo TV

 

Buffalo Bills Vs Indianapolis Colts Odds, Spread, Moneyline

Moneyline: Buffalo Bills (-197) vs Indianapolis Colts (+172)

Spread: Buffalo Bills -4.5 (+104) vs Indianapolis Colts +4.5 (-117)

Total (O/U): Buffalo Bills (o46.5) vs Indianapolis Colts (u46.5)

*All odds are subject to change depending on the time of this posting

Buffalo Bills
Bills quarterback Josh Allen waits before throwing to a receiver during second half action at Highmark Stadium on Nov. 3, 2024.

Buffalo Bills

The Buffalo Bills played the Miami Dolphins last week and won the game with a final score of 30-27. Against Miami, Buffalo’s QB Josh Allen went for 235 yards, completing 25 passes out of 39. Allen managed to score three touchdowns in that game, with a single interception. James Cook took care of Buffalo’s rushing with ten carries for 44 yards. On defense, Ray Davis managed a pair of receptions for 70 yards, along with a solo TD.

Top 3 Players

Josh Allen: 2,001 Yds, 17 TD, 2 INT

James Cook: 109 Car, 496 Yds, 7 TD

Khalil Shakir: 42 rec, 471 Yds, 2 TD

 

Indianapolis Colts

The Indianapolis Colts are coming here after playing the Minnesota Vikings in the previous week. In that game, Indianapolis’ Joe Flacco led the offense with 16 pass-completions for 27 attempts in 179 yards. Flacco managed a solo interception in that game. In terms of rushing, Jonathan Taylor led the team with 13 carries for 48 yards, while Josh Downs took charge of the defense with six receptions for 60 yards.

Top 3 Players

Anthony Richardson: 958 Yds, 4 TD, 7 INT

Jonathan Taylor: 105 Car, 502 Yds, 5 TD

Alec Pierce: 19 Rec, 435 Yds, 3 TD

 

Buffalo Bills Vs Indianapolis Colts Injury Report

Buffalo Bills

Amari Cooper (WR) Is “?” Sunday vs Indianapolis, Wrist

Matt Milano (LB) IR, Biceps

Casey Toohill (DE) Is “?” Sunday vs Indianapolis, Knee

Reggie Gilliam (RB) Is “?” Sunday vs Indianapolis, Hip

Shane Buechele (QB) IR, Neck

Christian Benford (CB) Is “?” Sunday vs Indianapolis, Wrist

DeWayne Carter (DT) IR, Wrist

Keon Coleman (WR) Left last game, is “?” Sunday vs Indianapolis, Wrist

Travis Clayton (T) IR, Shoulder

Tylan Grable (T) IR, Groin

 

Indianapolis Colts

Samson Ebukam (LB) IR, Achilles

Tyquan Lewis (DT) IR, Undisclosed

Juwann Winfree (WR) IR, Undisclosed

Will Fries (G) IR, Tibia

Bernhard Raimann (T) Is “?” Sunday vs Buffalo, Concussion

Jelani Woods (TE) IR, Toe

Trevor Denbow (S) IR, Knee

Wesley French (C) IR, Ankle

JuJu Brents (CB) IR, MCL

Daniel Scott (S) IR, Achilles

Jaylon Carlies (S) IR, Calf

Ryan Coll (T) IR, Undisclosed

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Indianapolis Colts quarterback Joe Flacco (15) tosses the ball to Indianapolis Colts running back Jonathan Taylor (28) on Sunday, Sept. 29, 2024, during a game against the Pittsburgh Steelers at Lucas Oil Stadium in Indianapolis.

Buffalo Bills Vs Indianapolis Colts Betting Trends

Buffalo Bills

Buffalo are 13-3 SU in their last 16 games.

Buffalo are 2-4 ATS in their last 6 games against Indianapolis.

Buffalo are 4-9 SU in their last 13 games against Indianapolis.

The total has gone UNDER in 5 of Buffalo’s last 6 games on the road.

Buffalo are 0-6 SU in their last 6 games when playing on the road against Indianapolis.

Buffalo are 11-3 SU in their last 14 games against an opponent in the American Football Conference.

The total has gone OVER in 4 of Buffalo’s last 6 games against an opponent in the American Football Conference South division.

Buffalo are 1-5 ATS in their last 6 games played in November.

Indianapolis Colts

Indianapolis are 6-1 ATS in their last 7 games.

The total has gone UNDER in 4 of Indianapolis’ last 5 games.

The total has gone UNDER in 7 of Indianapolis’ last 10 games against Buffalo.

Indianapolis are 4-1 ATS in their last 5 games at home.

Indianapolis are 6-0 SU in their last 6 games when playing at home against Buffalo.

Indianapolis are 6-0 ATS in their last 6 games against an opponent in the American Football Conference.

Indianapolis are 6-1 SU in their last 7 games against an opponent in the American Football Conference East division.

The total has gone UNDER in 4 of Indianapolis’ last 6 games played in November.

The total has gone UNDER in 6 of Indianapolis’ last 8 games played on a Sunday.

 

Buffalo Bills Vs Indianapolis Colts Summary and Prediction

The Buffalo Bills are definitely stronger than the Indianapolis Colts on both ends, and will easily dominate the home-team. The Colts have suffered in the past against Buffalo, and will continue here as well. Take the Buffalo Bills to win with a final score of 24-20.

Moneyline: Bills (-197)

Spread: Under 4.5

Total: Over 46.5

Predicted Score: 24-20, Bills win.

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Bills Kaiir Elam celebrates his fumble recovery against Miami during second half action at Highmark Stadium on Nov. 3, 2024.

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Follow me on X at @ErnestLeo, and follow us at @HardwoodHeroics and @GridironHeroics. You can also reach out to Ernest Hernandez via email at ernestleo@gmail.com. To read more of our articles and keep up to date on the latest sports news, click here!

Ernest also manages a YouTube account called Sports On Air with over 103 thousand subscribers. The channel contains interviews predominantly from the Philippine Basketball Association. They can be reached at sportsonairph@gmail.com.

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About Ernest Leo Hernandez

Ernest has been a sportswriter for more than 10 years and has written for the top broadsheets in the Philippines, like Manila Bulletin and Philippine Star. He also wrote for NBA.com Philippines and had a two-year stint with Sportskeeda before landing at Gridiron Heroics. Aside from writing, Ernest is also a sportscaster, radio host and manages a YouTube channel, Sports On Air, which has over 100 thousand subscribers.

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