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Denver Broncos, Alex Singleton, NFL
November 16, 2025 By  NFL, Denver Broncos

“The First Positive NFL Drug Test That’s Great!”: Fans React After Discovery of Cancerous Tumor on Broncos’ Alex Singleton

Denver Broncos linebacker Alex Singleton revealed this week that a routine NFL drug test led to the discovery of a testicular tumor, prompting surgery the day after he played in a primetime game. The unexpected turn has prompted an outpouring of relief and support from fans who called the positive test result a rare piece of good news.

Singleton’s elevated hCG level was flagged during a random screening, which can indicate performance‑enhancing drug use but is also a marker for certain cancers. He sought medical evaluation, underwent imaging that confirmed a tumour, played in the Broncos’ win over the Raiders and then had surgery the following day. Team doctors said early detection appears to have kept the disease localized and the prognosis is optimistic.

Denver Broncos, Alex Singleton, NFL
Bills running back Devin Singletary runs over the tackle of DenverÕs Alex Singleton during the Bills preseason game against Denver Saturday, Aug. 20, 2022 at Highmark Stadium. Buffalo won the game 42-15.
Sd 082022 Bills 10 Spts

Social media users reacted strongly to the sequence of events, with many noting the irony that a positive drug test saved a life. Supporters praised Singleton’s transparency and urged others to prioritise regular checkups and screening. Commenters also lauded the Broncos for quick medical coordination after the abnormal result and for the player’s decision to share his experience publicly to encourage awareness.

Sports outlets highlighted the procedural pathways that made the diagnosis possible: league drug programs, rapid team medical response and expedited specialist referrals. Analysts framed Singleton’s case as a reminder that testing systems intended to police substance use can have unintended health benefits in exceptional circumstances. Medical experts cautioned that while this outcome was fortunate, broad public health lessons remain about self‑exams and early consultation for unusual symptoms.

NFL Fans React Positively to Denver Broncos Star Alex Singleton’s Health Update

Denver Broncos, Alex Singleton, NFL
August 19, 2023; Santa Clara, California, USA; San Francisco 49ers running back Jordan Mason (24) is tackled by Denver Broncos cornerback Ja’Quan McMillian (35) and linebacker Alex Singleton (49) during the second quarter at Levi’s Stadium. Mandatory Credit: Kyle Terada-USA TODAY Sports

Fans have shared their thoughts about Singleton’s health update regarding his cancerous tumor. These reactions can be seen in a post shared by Adam Schefter on X.

 

View this post on Instagram

 

A post shared by Adam Schefter (@adamschefter)

“Jeeze! The first positive NFL drug test that’s great!” a fan said. “Damn, glad they caught it!” another shared.

A supporter mentioned, “Glad they caught it, hope it’s a quick recovery.”

“IDGAF what team you play or root for, a win is a win. Love ya see positive news,” a follower remarked.

“Wild, glad they caught it and prayers out to Alex and the family,” a commenter posted.

“Bro after reading the first sentence I thought he was cooked lol glad he’s gonna be ok,” a sixth social media user reacted.

Broncos teammates and opponents alike sent messages of support, and the club has provided resources to help Singleton recover. He is expected to miss the next game but expressed hope to return after further pathology and follow‑up scans. Coaches said the team will manage on‑field adjustments while prioritising his health.

Denver Broncos, Alex Singleton, NFL
Oct 5, 2025; Philadelphia, Pennsylvania, USA; Denver Broncos linebacker Alex Singleton (49) during warmups against the Philadelphia Eagles at Lincoln Financial Field. Mandatory Credit: Eric Hartline-Imagn Images

The story has resonated beyond sports, prompting conversations about stigma, screening and the multiple roles testing programmes play in athlete care. For many NFL fans, the unexpected diagnosis and positive outcome turned what is usually seen as punitive monitoring into a moment of gratitude and a call to action for early detection.

Denver Broncos, Alex Singleton, NFL
Feb 6, 2025; New Orleans, LA, USA; Alex Singleton and his mother Kim Singleton on the red carpet before Super Bowl LIX NFL Honors at Saenger Theatre. Mandatory Credit: Kirby Lee-Imagn Images

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About Angelo Guinhawa

Angelo Guinhawa is a veteran sports writer and editor who has been working in the industry for over 10 years now. He has worked for FOX Sports PH and several other reputable sports publications. His specialty is the NBA and the NFL, though he also covers the MLB, NHL and European top-flight football.

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